Cervical cancer remains one of the leading causes of cancer-related death among women globally, despite the availability of highly effective tools for prevention. Human papillomavirus (HPV) vaccination and HPV-based screening have demonstrated strong efficacy in reducing cervical cancer incidence and mortality. Nevertheless, their uptake and implementation remain uneven across regions, with the highest burden of disease persisting in low- and middle-income countries (LMICs).

A recent review published in ASCO Educational Book explores the challenges and opportunities associated with global cervical cancer elimination, offering insights that extend well beyond a single disease. The paper examines the evidence base for HPV vaccination and HPV-based screening, while critically assessing the health system, policy, and implementation barriers that limit their impact.

The review hlights how innovations developed for cervical cancer prevention—such as digital health platforms, mobile and community-based screening, and task-shifting—can serve as a model for strengthening primary and secondary prevention strategies for other cancers. Achieving the WHO’s 90–70–90 targets for cervical cancer elimination will require sustained policy commitment, health system strengthening, and international collaboration, but it also presents a unique opportunity to transform cancer prevention more broadly.

Read the full paper:
👉 https://ascopubs.org/doi/10.1200/EDBK-25-473702