Avoidable Deaths Through the Primary Prevention, Early Detection, and Curative Treatment of Cancer Worldwide

A Population-Based Study

Cancer Risk factors

Available Public Health and Clinical Interventions

The International Agency for Research on Cancer (IARC) has published new research estimating the global number of cancer deaths that could potentially be avoided through effective prevention measures, earlier diagnosis, and access to curative treatment. The population-based study examines worldwide cancer mortality and assesses how many deaths among individuals diagnosed with cancer might be prevented using currently available public health and clinical interventions.

 

Cancer Risk Factors

 

The analysis shows that approximately 4.5 million deaths among people diagnosed with cancer globally in 2022 could have been avoided. This represents nearly half of all cancer deaths in this population. The largest share of preventable deaths is linked to primary prevention, accounting for about 3.1 million deaths related to modifiable risk factors such as tobacco use, alcohol consumption, excess body weight, infections associated with cancer, and exposure to ultraviolet radiation.

 

Early Detection and Access to Treatment

In addition to prevention, the study highlights the critical role of early detection and access to treatment. Around 1.4 million deaths could potentially be avoided through improved screening programmes, timely diagnosis, and access to effective therapies. The findings show that cancers such as breast, colorectal, and prostate cancer contribute substantially to deaths that could be prevented through improved health care delivery.

 

Global Disparities

The research also emphasizes major global disparities. Low and middle income countries experience the highest burden of preventable cancer deaths because prevention programmes, screening coverage, and treatment services remain limited. The findings provide important evidence for governments and health organizations seeking to strengthen national cancer control strategies and expand prevention and early detection programmes.

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This project has received funding from the European Union’s EU4HEALTH Programme under the Grant Agreement no 101162959